Thymosin Alpha-1 Boosts Flu Vaccine Response in Elderly Adults

Thymosin alpha-1 as an adjunct to influenza vaccination improved antibody responses in elderly adults who typically have poor vaccine efficacy — addressing the age-related immune gap that makes elderly people vulnerable to flu.

Ershler, William B et al.·Annals of the New York Academy of Sciences·2007·Moderate EvidenceReview
RPEP-01224ReviewModerate Evidence2007RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Review
Evidence
Moderate Evidence
Sample
Not reported

What This Study Found

Thymosin alpha-1 as an influenza vaccine adjuvant improved seroconversion and antibody titers in elderly adults with normally impaired vaccine responses, addressing the immunosenescence that makes influenza vaccination less effective in the aged.

Key Numbers

How They Did This

review study on thymosin-alpha-1, immune-function.

Why This Research Matters

Relevant for thymosin-alpha-1, immune-function, anti-aging.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Thymosin alpha-1 as an influenza vaccine adjuvant improved seroconversion and antibody titers in elderly adults with normally impaired vaccine respons
Evidence Grade:
moderate evidence.
Study Age:
Published in 2007.
Original Title:
Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.
Published In:
Annals of the New York Academy of Sciences, 1112, 375-84 (2007)
Database ID:
RPEP-01224

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study

Summarizes existing research on a topic.

What do these levels mean? →

Frequently Asked Questions

What was studied?

Thymosin Alpha-1 Boosts Flu Vaccine Response in Elderly Adults

What was found?

Thymosin alpha-1 as an adjunct to influenza vaccination improved antibody responses in elderly adults who typically have poor vaccine efficacy — addressing the age-related immune gap that makes elderly people vulnerable to flu.

Read More on RethinkPeptides

Cite This Study

RPEP-01224·https://rethinkpeptides.com/research/RPEP-01224

APA

Ershler, William B; Gravenstein, Stefan; Geloo, Zeba S. (2007). Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.. Annals of the New York Academy of Sciences, 1112, 375-84.

MLA

Ershler, William B, et al. "Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.." Annals of the New York Academy of Sciences, 2007.

RethinkPeptides

RethinkPeptides Research Database. "Thymosin alpha 1 as an adjunct to influenza vaccination in t..." RPEP-01224. Retrieved from https://rethinkpeptides.com/research/ershler-2007-thymosin-alpha-1-as

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.