A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.

RPEP-107632025Douros, Jonathan D; Novikoff, Aaron; DuBois, Barent; Rohlfs, Rebecca; Mokrosinski, Jacek; Hogendorf, Wouter F J; Augustin, Robert; Merkestein, Myrte; Egaa Martini, Lene Brandt; Linderoth, Lars; Gerrard, Elliot; Kodra, Janos Tibor; Norlin, Jenny; Roed, Nikolaj Kulahin; Oldenburger, Anouk; Mowery, Stephanie A; Waldhoer, Maria; Perez-Tilve, Diego; Finan, Brian; Reedtz-Runge, Steffen; Müller, Timo D; Knerr, Patrick J

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A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.

Molecular metabolism, 100, 102124

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Douros, Jonathan D; Novikoff, Aaron; DuBois, Barent; Rohlfs, Rebecca; Mokrosinski, Jacek; Hogendorf, Wouter F J; Augustin, Robert; Merkestein, Myrte; Egaa Martini, Lene Brandt; Linderoth, Lars; Gerrard, Elliot; Kodra, Janos Tibor; Norlin, Jenny; Roed, Nikolaj Kulahin; Oldenburger, Anouk; Mowery, Stephanie A; Waldhoer, Maria; Perez-Tilve, Diego; Finan, Brian; Reedtz-Runge, Steffen; Müller, Timo D; Knerr, Patrick J. (2025). A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice.. Molecular metabolism, 100, 102124. https://doi.org/10.1016/j.molmet.2025.102124