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Study breakdown

GI Targets for Appetite Regulation in Humans: From Stomach Stretch to Gut Peptides

evidence
The takeaway

Gastrointestinal appetite targets span mechanoreceptors (stomach distension), gut peptides (GLP-1, PYY, CCK, ghrelin), nutrient sensors, and microbiome-derived signals — the complete GI appetite regulation toolkit.

Key finding

Gastrointestinal appetite targets span mechanoreceptors (stomach distension), gut peptides (GLP-1, PYY, CCK, ghrelin), nutrient sensors, and microbiom

What the researchers found

Gastrointestinal appetite targets span mechanoreceptors (stomach distension), gut peptides (GLP-1, PYY, CCK, ghrelin), nutrient sensors, and microbiome-derived signals — the complete GI appetite regulation toolkit.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
GI Targets for Appetite Regulation in Humans: From Stomach Stretch to Gut Peptides
What was found?
Gastrointestinal appetite targets span mechanoreceptors (stomach distension), gut peptides (GLP-1, PYY, CCK, ghrelin), nutrient sensors, and microbiome-derived signals — the complete GI appetite regulation toolkit.

Read the original research

Gastrointestinal targets of appetite regulation in humans.

Obesity reviews : an official journal of the International Association for the Study of Obesity, 11(3), 234-50

Citation

Delzenne, N; Blundell, J; Brouns, F; Cunningham, K; De Graaf, K; Erkner, A; Lluch, A; Mars, M; Peters, H P F; Westerterp-Plantenga, M. (2010). Gastrointestinal targets of appetite regulation in humans.. Obesity reviews : an official journal of the International Association for the Study of Obesity, 11(3), 234-50. https://doi.org/10.1111/j.1467-789X.2009.00707.x