GHRP-6 protected hypothalamic neurons from glutamate excitotoxicity through a caspase-independent mechanism, suggesting non-apoptotic neuroprotection distinct from classical anti-apoptotic pathways.
Key findingGHRP-6 protected hypothalamic neurons from glutamate excitotoxicity through a caspase-independent mechanism, suggesting non-apoptotic neuroprotection
What the researchers found
GHRP-6 protected hypothalamic neurons from glutamate excitotoxicity through a caspase-independent mechanism, suggesting non-apoptotic neuroprotection distinct from classical anti-apoptotic pathways.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I.
The European journal of neuroscience, 29(11), 2115-24
Citation
Delgado-Rubín, A; Chowen, Julie A; Argente, Jesús; Frago, Laura M. (2009). Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I.. The European journal of neuroscience, 29(11), 2115-24. https://doi.org/10.1111/j.1460-9568.2009.06770.x