Motilin and Ghrelin as Prokinetic Drug Targets for Gastroparesis and GI Motility Disorders

Motilin and ghrelin receptor agonists are prokinetic drug candidates for gastroparesis, with ghrelin's dual appetite + motility effects offering unique therapeutic advantages over pure prokinetics.

De Smet, Betty et al.·Pharmacology & therapeutics·2009·
RPEP-014702009RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Motilin and ghrelin receptor agonists are prokinetic drug candidates for gastroparesis, with ghrelin's dual appetite + motility effects offering unique therapeutic advantages over pure prokinetics.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Motilin and ghrelin receptor agonists are prokinetic drug candidates for gastroparesis, with ghrelin's dual appetite + motility effects offering uniqu
Evidence Grade:
emerging evidence.
Study Age:
Published in 2009.
Original Title:
Motilin and ghrelin as prokinetic drug targets.
Published In:
Pharmacology & therapeutics, 123(2), 207-23 (2009)
Database ID:
RPEP-01470

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Motilin and Ghrelin as Prokinetic Drug Targets for Gastroparesis and GI Motility Disorders

What was found?

Motilin and ghrelin receptor agonists are prokinetic drug candidates for gastroparesis, with ghrelin's dual appetite + motility effects offering unique therapeutic advantages over pure prokinetics.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01470·https://rethinkpeptides.com/research/RPEP-01470

APA

De Smet, Betty; Mitselos, Anna; Depoortere, Inge. (2009). Motilin and ghrelin as prokinetic drug targets.. Pharmacology & therapeutics, 123(2), 207-23. https://doi.org/10.1016/j.pharmthera.2009.04.004

MLA

De Smet, Betty, et al. "Motilin and ghrelin as prokinetic drug targets.." Pharmacology & therapeutics, 2009. https://doi.org/10.1016/j.pharmthera.2009.04.004

RethinkPeptides

RethinkPeptides Research Database. "Motilin and ghrelin as prokinetic drug targets." RPEP-01470. Retrieved from https://rethinkpeptides.com/research/de-2009-motilin-and-ghrelin-as

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.