Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.

Daveson, A James M et al.·EBioMedicine·2017·
RPEP-032622017RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Key Numbers

How They Did This

Why This Research Matters

What This Study Doesn't Tell Us

Trust & Context

Original Title:
Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.
Published In:
EBioMedicine, 26, 78-90 (2017)
Database ID:
RPEP-03262

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
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Cite This Study

RPEP-03262·https://rethinkpeptides.com/research/RPEP-03262

APA

Daveson, A James M; Ee, Hooi C; Andrews, Jane M; King, Timothy; Goldstein, Kaela E; Dzuris, John L; MacDougall, James A; Williams, Leslie J; Treohan, Anita; Cooreman, Michael P; Anderson, Robert P. (2017). Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.. EBioMedicine, 26, 78-90. https://doi.org/10.1016/j.ebiom.2017.11.018

MLA

Daveson, A James M, et al. "Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.." EBioMedicine, 2017. https://doi.org/10.1016/j.ebiom.2017.11.018

RethinkPeptides

RethinkPeptides Research Database. "Epitope-Specific Immunotherapy Targeting CD4-Positive T Cell..." RPEP-03262. Retrieved from https://rethinkpeptides.com/research/daveson-2017-epitopespecific-immunotherapy-targeting-cd4positive

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Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.