Mitochondria-Targeted Peptide SS-31 Treats High Blood Pressure Heart Damage

The mitochondria-targeted antioxidant peptide SS-31 ameliorated hypertensive cardiomyopathy in rats, reducing cardiac fibrosis, hypertrophy, and diastolic dysfunction — protecting the heart from high blood pressure damage.

RPEP-017512011RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

The mitochondria-targeted antioxidant peptide SS-31 ameliorated hypertensive cardiomyopathy in rats, reducing cardiac fibrosis, hypertrophy, and diastolic dysfunction — protecting the heart from high blood pressure damage.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding The mitochondria-targeted antioxidant peptide SS-31 ameliorated hypertensive cardiomyopathy in rats, reducing cardiac fibrosis, hypertrophy, and diast
Evidence Grade:
emerging evidence.
Study Age:
Published in 2011.
Original Title:
Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy.
Published In:
Journal of the American College of Cardiology, 58(1), 73-82 (2011)
Database ID:
RPEP-01751

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Mitochondria-Targeted Peptide SS-31 Treats High Blood Pressure Heart Damage

What was found?

The mitochondria-targeted antioxidant peptide SS-31 ameliorated hypertensive cardiomyopathy in rats, reducing cardiac fibrosis, hypertrophy, and diastolic dysfunction — protecting the heart from high blood pressure damage.

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Cite This Study

RPEP-01751·https://rethinkpeptides.com/research/RPEP-01751

APA

Dai, Dao-Fu; Chen, Tony; Szeto, Hazel; Nieves-Cintrón, Madeline; Kutyavin, Vassily; Santana, Luis F; Rabinovitch, Peter S. (2011). Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy.. Journal of the American College of Cardiology, 58(1), 73-82. https://doi.org/10.1016/j.jacc.2010.12.044

MLA

Dai, Dao-Fu, et al. "Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy.." Journal of the American College of Cardiology, 2011. https://doi.org/10.1016/j.jacc.2010.12.044

RethinkPeptides

RethinkPeptides Research Database. "Mitochondrial targeted antioxidant Peptide ameliorates hyper..." RPEP-01751. Retrieved from https://rethinkpeptides.com/research/dai-2011-mitochondrial-targeted-antioxidant-peptide

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.