Glucagon-like peptide 1 (GLP-1) receptor agonists as a protective factor for incident depression in patients with diabetes mellitus: A systematic review.
Quick Facts
What This Study Found
Two out of four studies showed a significant reduction in depression risk with GLP-1 receptor agonists.
Key Numbers
How They Did This
A systematic review of four retrospective observational studies on GLP-1 receptor agonists and depression risk in diabetes patients.
Why This Research Matters
Understanding the potential mental health benefits of diabetes medications could improve patient care. Further research may lead to better treatment options for preventing depression in diabetic patients.
What This Study Doesn't Tell Us
The study faced high interstudy heterogeneity, limited literature, and a lack of controlled trials.
Trust & Context
- Original Title:
- Glucagon-like peptide 1 (GLP-1) receptor agonists as a protective factor for incident depression in patients with diabetes mellitus: A systematic review.
- Published In:
- Journal of psychiatric research, 164, 80-89 (2023)
- Authors:
- Cooper, Daniel H, Ramachandra, Ranuk, Ceban, Felicia, Di Vincenzo, Joshua D, Rhee, Taeho Greg, Mansur, Rodrigo B, Teopiz, Kayla M, Gill, Hartej, Ho, Roger, Cao, Bing, Lui, Leanna M W, Jawad, Muhammad Youshay, Arsenault, Juliet, Le, Gia Han, Ramachandra, Diluk, Guo, Ziji, McIntyre, Roger S
- Database ID:
- RPEP-06810
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06810APA
Cooper, Daniel H; Ramachandra, Ranuk; Ceban, Felicia; Di Vincenzo, Joshua D; Rhee, Taeho Greg; Mansur, Rodrigo B; Teopiz, Kayla M; Gill, Hartej; Ho, Roger; Cao, Bing; Lui, Leanna M W; Jawad, Muhammad Youshay; Arsenault, Juliet; Le, Gia Han; Ramachandra, Diluk; Guo, Ziji; McIntyre, Roger S. (2023). Glucagon-like peptide 1 (GLP-1) receptor agonists as a protective factor for incident depression in patients with diabetes mellitus: A systematic review.. Journal of psychiatric research, 164, 80-89. https://doi.org/10.1016/j.jpsychires.2023.05.041
MLA
Cooper, Daniel H, et al. "Glucagon-like peptide 1 (GLP-1) receptor agonists as a protective factor for incident depression in patients with diabetes mellitus: A systematic review.." Journal of psychiatric research, 2023. https://doi.org/10.1016/j.jpsychires.2023.05.041
RethinkPeptides
RethinkPeptides Research Database. "Glucagon-like peptide 1 (GLP-1) receptor agonists as a prote..." RPEP-06810. Retrieved from https://rethinkpeptides.com/research/cooper-2023-glucagonlike-peptide-1-glp1
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.