Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial.

RPEP-103782025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Key Numbers

How They Did This

Why This Research Matters

What This Study Doesn't Tell Us

Trust & Context

Original Title:
Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial.
Published In:
Reproductive biology and endocrinology : RB&E, 23(1), 108 (2025)
Database ID:
RPEP-10378

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
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Cite This Study

RPEP-10378·https://rethinkpeptides.com/research/RPEP-10378

APA

Chen, Haiyan; Lei, Xiaohui; Yang, Zhuoran; Xu, Yuxin; Liu, Dongfang; Wang, Cong; Du, Hu. (2025). Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial.. Reproductive biology and endocrinology : RB&E, 23(1), 108. https://doi.org/10.1186/s12958-025-01447-3

MLA

Chen, Haiyan, et al. "Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial.." Reproductive biology and endocrinology : RB&E, 2025. https://doi.org/10.1186/s12958-025-01447-3

RethinkPeptides

RethinkPeptides Research Database. "Effects of combined metformin and semaglutide therapy on bod..." RPEP-10378. Retrieved from https://rethinkpeptides.com/research/chen-2025-effects-of-combined-metformin

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Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.