This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
The iRGD-PSS@PBAE@JQ1/ORI nanoparticles significantly enhanced tumor targeting and cellular internalization.
Why it matters
This research addresses the limitations of current breast cancer therapies by introducing a novel delivery system that improves drug efficacy. It could pave the way for more effective treatments in the future.
How the study worked
The study involved the development and evaluation of a peptide-modified nano-delivery system in both laboratory and animal models.
What this study cannot tell us
The study primarily focuses on in vitro and in vivo models, and further research is needed to confirm efficacy in human patients.
Read the original research
iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.
International journal of nanomedicine, 17, 617-633
Citation
Chen, Bowei; Liu, Xiaohong; Li, Yunan; Shan, Tianhe; Bai, Liya; Li, Chunyu; Wang, Yinsong. (2022). iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.. International journal of nanomedicine, 17, 617-633. https://doi.org/10.2147/IJN.S343902