iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.
Quick Facts
What This Study Found
The iRGD-PSS@PBAE@JQ1/ORI nanoparticles significantly enhanced tumor targeting and cellular internalization.
Key Numbers
How They Did This
The study involved the development and evaluation of a peptide-modified nano-delivery system in both laboratory and animal models.
Why This Research Matters
This research addresses the limitations of current breast cancer therapies by introducing a novel delivery system that improves drug efficacy. It could pave the way for more effective treatments in the future.
What This Study Doesn't Tell Us
The study primarily focuses on in vitro and in vivo models, and further research is needed to confirm efficacy in human patients.
Trust & Context
- Original Title:
- iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.
- Published In:
- International journal of nanomedicine, 17, 617-633 (2022)
- Authors:
- Chen, Bowei, Liu, Xiaohong, Li, Yunan, Shan, Tianhe, Bai, Liya, Li, Chunyu, Wang, Yinsong
- Database ID:
- RPEP-06039
Evidence Hierarchy
Read More on RethinkPeptides
Related articles coming soon.
Cite This Study
https://rethinkpeptides.com/research/RPEP-06039APA
Chen, Bowei; Liu, Xiaohong; Li, Yunan; Shan, Tianhe; Bai, Liya; Li, Chunyu; Wang, Yinsong. (2022). iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.. International journal of nanomedicine, 17, 617-633. https://doi.org/10.2147/IJN.S343902
MLA
Chen, Bowei, et al. "iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer.." International journal of nanomedicine, 2022. https://doi.org/10.2147/IJN.S343902
RethinkPeptides
RethinkPeptides Research Database. "iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System..." RPEP-06039. Retrieved from https://rethinkpeptides.com/research/chen-2022-irgd-tumorpenetrating-peptidemodified-nanodelivery
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.