This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
Body mass increased by 6.0%, while total testosterone decreased by 62.3%.
Why it matters
Understanding the effects of these compounds is crucial as they are increasingly used among recreational athletes. The negative impacts on health markers highlight the risks involved.
How the study worked
A 25-year-old male took LGD-4033 (10 mg) and MK-677 (15 mg) daily for 5 weeks, with assessments of body composition and biomarkers before, during, and after the cycle.
What this study cannot tell us
The study is based on a single case, limiting the generalizability of the findings.
Read the original research
LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.
Experimental physiology, 107(12), 1467-1476
Citation
Cardaci, Thomas D; Machek, Steven B; Wilburn, Dylan T; Heileson, Jeffery L; Harris, Dillon R; Cintineo, Harry P; Willoughby, Darryn S. (2022). LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.. Experimental physiology, 107(12), 1467-1476. https://doi.org/10.1113/EP090741