LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.
Quick Facts
What This Study Found
Body mass increased by 6.0%, while total testosterone decreased by 62.3%.
Key Numbers
How They Did This
A 25-year-old male took LGD-4033 (10 mg) and MK-677 (15 mg) daily for 5 weeks, with assessments of body composition and biomarkers before, during, and after the cycle.
Why This Research Matters
Understanding the effects of these compounds is crucial as they are increasingly used among recreational athletes. The negative impacts on health markers highlight the risks involved.
What This Study Doesn't Tell Us
The study is based on a single case, limiting the generalizability of the findings.
Trust & Context
- Original Title:
- LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.
- Published In:
- Experimental physiology, 107(12), 1467-1476 (2022)
- Authors:
- Cardaci, Thomas D, Machek, Steven B, Wilburn, Dylan T, Heileson, Jeffery L, Harris, Dillon R, Cintineo, Harry P, Willoughby, Darryn S
- Database ID:
- RPEP-06030
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06030APA
Cardaci, Thomas D; Machek, Steven B; Wilburn, Dylan T; Heileson, Jeffery L; Harris, Dillon R; Cintineo, Harry P; Willoughby, Darryn S. (2022). LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.. Experimental physiology, 107(12), 1467-1476. https://doi.org/10.1113/EP090741
MLA
Cardaci, Thomas D, et al. "LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.." Experimental physiology, 2022. https://doi.org/10.1113/EP090741
RethinkPeptides
RethinkPeptides Research Database. "LGD-4033 and MK-677 use impacts body composition, circulatin..." RPEP-06030. Retrieved from https://rethinkpeptides.com/research/cardaci-2022-lgd4033-and-mk677-use
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.