This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
Serum vitamin D levels increased from 45.1 to 93.5 nmoL/L, and AD severity decreased from 41.4 to 31.5 SCORAD.
Why it matters
This research highlights the potential of vitamin D as a simple intervention to improve skin health in children with eczema, which could lead to better management strategies.
How the study worked
An open-label study with 22 children receiving weekly oral vitamin D3 for six weeks, measuring skin and serum markers.
What this study cannot tell us
The study had a small sample size and lacked a control group, which may affect the reliability of the findings.
Read the original research
Oral vitamin D modulates the epidermal expression of the vitamin D receptor and cathelicidin in children with atopic dermatitis.
Archives of dermatological research, 315(4), 761-770
Citation
Cabalín, Carolina; Pérez-Mateluna, Guillermo; Iturriaga, Carolina; Camargo, Carlos A; Borzutzky, Arturo. (2023). Oral vitamin D modulates the epidermal expression of the vitamin D receptor and cathelicidin in children with atopic dermatitis.. Archives of dermatological research, 315(4), 761-770. https://doi.org/10.1007/s00403-022-02416-1