Beyond KPV: The Full Anti-Inflammatory Potential of Alpha-MSH C-Terminal Peptides

Alpha-MSH C-terminal peptides beyond the known KPV pharmacophore showed anti-inflammatory activity, revealing the C-terminal signal extends further than the classic tripeptide — expanded anti-inflammatory peptide toolkit.

Brzoska, Thomas et al.·Advances in experimental medicine and biology·2010·
RPEP-015922010RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Alpha-MSH C-terminal peptides beyond the known KPV pharmacophore showed anti-inflammatory activity, revealing the C-terminal signal extends further than the classic tripeptide — expanded anti-inflammatory peptide toolkit.

Key Numbers

How They Did This

research study.

Why This Research Matters

Relevant for peptide research.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.

Trust & Context

Key Stat:
Key finding Alpha-MSH C-terminal peptides beyond the known KPV pharmacophore showed anti-inflammatory activity, revealing the C-terminal signal extends further th
Evidence Grade:
emerging evidence.
Study Age:
Published in 2010.
Original Title:
Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore.
Published In:
Advances in experimental medicine and biology, 681, 107-16 (2010)
Database ID:
RPEP-01592

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What was studied?

Beyond KPV: The Full Anti-Inflammatory Potential of Alpha-MSH C-Terminal Peptides

What was found?

Alpha-MSH C-terminal peptides beyond the known KPV pharmacophore showed anti-inflammatory activity, revealing the C-terminal signal extends further than the classic tripeptide — expanded anti-inflammatory peptide toolkit.

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-01592·https://rethinkpeptides.com/research/RPEP-01592

APA

Brzoska, Thomas; Böhm, Markus; Lügering, Andreas; Loser, Karin; Luger, Thomas A. (2010). Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore.. Advances in experimental medicine and biology, 681, 107-16. https://doi.org/10.1007/978-1-4419-6354-3_8

MLA

Brzoska, Thomas, et al. "Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore.." Advances in experimental medicine and biology, 2010. https://doi.org/10.1007/978-1-4419-6354-3_8

RethinkPeptides

RethinkPeptides Research Database. "Terminal signal: anti-inflammatory effects of α-melanocyte-s..." RPEP-01592. Retrieved from https://rethinkpeptides.com/research/brzoska-2010-terminal-signal-antiinflammatory-effects

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.