Porcine pepsinogen was rationally redesigned to incorporate an antimicrobial peptide sequence, creating a fusion protein that retains both digestive enzyme activity and antibacterial properties — a dual-function gastric protector.
Key findingPorcine pepsinogen was rationally redesigned to incorporate an antimicrobial peptide sequence, creating a fusion protein that retains both digestive e
What the researchers found
Porcine pepsinogen was rationally redesigned to incorporate an antimicrobial peptide sequence, creating a fusion protein that retains both digestive enzyme activity and antibacterial properties — a dual-function gastric protector.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Rational redesign of porcine pepsinogen containing an antimicrobial peptide.
Protein engineering, design & selection : PEDS, 23(9), 711-9
Citation
Bryksa, Brian C; Horimoto, Yasumi; Yada, Rickey Y. (2010). Rational redesign of porcine pepsinogen containing an antimicrobial peptide.. Protein engineering, design & selection : PEDS, 23(9), 711-9. https://doi.org/10.1093/protein/gzq039