Understanding Ghrelin Through GHS-R1a Agonists and Antagonists: The Receptor Pharmacology Toolbox
Comprehensive review of GHS-R1a receptor pharmacology tools — agonists, antagonists, inverse agonists — revealing the receptor's role in both GH secretion and feeding, with implications for separating these functions therapeutically.
Quick Facts
What This Study Found
GHS-R1a pharmacological tools (agonists, antagonists, inverse agonists) revealed the receptor controls both GH secretion and feeding behavior, with receptor modification studies suggesting these functions may be partially separable for therapeutic benefit.
Key Numbers
How They Did This
review study.
Why This Research Matters
Relevant for ghrp, weight-loss, receptor-signaling.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding GHS-R1a pharmacological tools (agonists, antagonists, inverse agonists) revealed the receptor controls both GH secretion and feeding behavior, with re
- Evidence Grade:
- moderate evidence.
- Study Age:
- Published in 2008.
- Original Title:
- Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands.
- Published In:
- Eating and weight disorders : EWD, 13(3), e67-74 (2008)
- Authors:
- Bresciani, E, Tamiazzo, L, Torsello, A(3), Bulgarelli, I, Rapetti, D, Caporali, S, Perrissoud, D, Moulin, A, Fehrentz, J A, Martinez, J, Locatelli, V
- Database ID:
- RPEP-01315
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What was studied?
Understanding Ghrelin Through GHS-R1a Agonists and Antagonists: The Receptor Pharmacology Toolbox
What was found?
Comprehensive review of GHS-R1a receptor pharmacology tools — agonists, antagonists, inverse agonists — revealing the receptor's role in both GH secretion and feeding, with implications for separating these functions therapeutically.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-01315APA
Bresciani, E; Tamiazzo, L; Torsello, A; Bulgarelli, I; Rapetti, D; Caporali, S; Perrissoud, D; Moulin, A; Fehrentz, J A; Martinez, J; Locatelli, V. (2008). Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands.. Eating and weight disorders : EWD, 13(3), e67-74.
MLA
Bresciani, E, et al. "Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands.." Eating and weight disorders : EWD, 2008.
RethinkPeptides
RethinkPeptides Research Database. "Ghrelin control of GH secretion and feeding behaviour: the r..." RPEP-01315. Retrieved from https://rethinkpeptides.com/research/bresciani-2008-ghrelin-control-of-gh
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.