Cardiac kappa-opioid receptor stimulation affected systolic function differently in hypertensive versus normotensive rat hearts, revealing disease-state-dependent opioid cardiac pharmacology.
Key findingCardiac kappa-opioid receptor stimulation affected systolic function differently in hypertensive versus normotensive rat hearts, revealing disease-sta
What the researchers found
Cardiac kappa-opioid receptor stimulation affected systolic function differently in hypertensive versus normotensive rat hearts, revealing disease-state-dependent opioid cardiac pharmacology.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation.
American journal of physiology. Heart and circulatory physiology, 296(4), H967-75
Citation
Bolte, Craig; Newman, Gilbert; Schultz, Jo El J. (2009). Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation.. American journal of physiology. Heart and circulatory physiology, 296(4), H967-75. https://doi.org/10.1152/ajpheart.00909.2008