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Study breakdown

Synthesizing a Kidney Disease Glycopeptide Vaccine Target: Tn Antigen for IgA Nephropathy

evidence
The takeaway

Solid-phase synthesis of a pentavalent GalNAc glycopeptide representing the IgA nephropathy-associated Tn antigen enables research into this kidney disease's immune mechanism and potential vaccine approaches.

Key finding

Solid-phase synthesis of a pentavalent GalNAc glycopeptide representing the IgA nephropathy-associated Tn antigen enables research into this kidney di

What the researchers found

Solid-phase synthesis of a pentavalent GalNAc glycopeptide representing the IgA nephropathy-associated Tn antigen enables research into this kidney disease's immune mechanism and potential vaccine approaches.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Synthesizing a Kidney Disease Glycopeptide Vaccine Target: Tn Antigen for IgA Nephropathy
What was found?
Solid-phase synthesis of a pentavalent GalNAc glycopeptide representing the IgA nephropathy-associated Tn antigen enables research into this kidney disease's immune mechanism and potential vaccine approaches.

Read the original research

Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region.

Carbohydrate research, 345(14), 1998-2003

Citation

Bolscher, Jan G M; Brevoord, Judith; Nazmi, Kamran; Ju, Tongzhong; Veerman, Enno C I; van Wijk, Joanna A E; Cummings, Richard D; van Die, Irma. (2010). Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region.. Carbohydrate research, 345(14), 1998-2003. https://doi.org/10.1016/j.carres.2010.07.022