BPC-157 counteracted morphine-induced analgesia in mice, directly demonstrating BPC-157 interacts with the opioid system — blocking exogenous opioid effects consistent with its own distinct analgesic mechanism.
Key findingBPC-157 blocked morphine-induced analgesia in mice, directly demonstrating interaction with the opioid system — confirming BPC-157's pharmacological r
What the researchers found
BPC-157 blocked morphine-induced analgesia in mice, directly demonstrating interaction with the opioid system — confirming BPC-157's pharmacological relationship with opioid pathways and consistent with its known dopaminergic and GABAergic system modulation.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2009.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
- Clinical translation to evaluate.
Common questions
What was studied?
What was found?
Read the original research
Gastric pentadecapeptide BPC 157 counteracts morphine-induced analgesia in mice.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 60 Suppl 7, 177-81
Citation
Boban Blagaic, A; Turcic, P; Blagaic, V; Dubovecak, M; Jelovac, N; Zemba, M; Radic, B; Becejac, T; Stancic Rokotov, D; Sikiric, P. (2009). Gastric pentadecapeptide BPC 157 counteracts morphine-induced analgesia in mice.. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 60 Suppl 7, 177-81.