Tirzepatide leads to weight reduction in people with obesity due to MC4R deficiency.

Bhatnagar, Pallav et al.·Nature medicine·2025·
RPEP-101502025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Not classified
Evidence
Not graded
Sample
Not reported

What This Study Found

Key Numbers

How They Did This

Why This Research Matters

What This Study Doesn't Tell Us

Trust & Context

Original Title:
Tirzepatide leads to weight reduction in people with obesity due to MC4R deficiency.
Published In:
Nature medicine, 31(10), 3294-3296 (2025)
Database ID:
RPEP-10150

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Read More on RethinkPeptides

Related articles coming soon.

Cite This Study

RPEP-10150·https://rethinkpeptides.com/research/RPEP-10150

APA

Bhatnagar, Pallav; Ahmad, Nadia N; Li, Xuan; Coghlan, Matthew; Kaplan, Lee M; Farooqi, I Sadaf. (2025). Tirzepatide leads to weight reduction in people with obesity due to MC4R deficiency.. Nature medicine, 31(10), 3294-3296. https://doi.org/10.1038/s41591-025-03913-2

MLA

Bhatnagar, Pallav, et al. "Tirzepatide leads to weight reduction in people with obesity due to MC4R deficiency.." Nature medicine, 2025. https://doi.org/10.1038/s41591-025-03913-2

RethinkPeptides

RethinkPeptides Research Database. "Tirzepatide leads to weight reduction in people with obesity..." RPEP-10150. Retrieved from https://rethinkpeptides.com/research/bhatnagar-2025-tirzepatide-leads-to-weight

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.