Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vaccination effect) that protected against distant tumor challenge.
Key findingIntratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vacc
What the researchers found
Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vaccination effect) that protected against distant tumor challenge.
Why it matters
Relevant for peptide research.
How the study worked
research study.
What this study cannot tell us
See abstract.
How to read the evidence
emerging evidence.
When this study was published
Published in 2010.
The bigger picture
Advances peptide research.
Questions still open
- Further research needed.
Common questions
What was studied?
What was found?
Read the original research
Therapeutic vaccination against a murine lymphoma by intratumoral injection of a cationic anticancer peptide.
Cancer immunology, immunotherapy : CII, 59(8), 1285-94
Citation
Berge, Gerd; Eliassen, Liv Tone; Camilio, Ketil Andre; Bartnes, Kristian; Sveinbjørnsson, Baldur; Rekdal, Oystein. (2010). Therapeutic vaccination against a murine lymphoma by intratumoral injection of a cationic anticancer peptide.. Cancer immunology, immunotherapy : CII, 59(8), 1285-94. https://doi.org/10.1007/s00262-010-0857-6