Injecting Anticancer Peptides Directly Into Tumors Creates a Vaccine-Like Anti-Cancer Immune Response
Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vaccination effect) that protected against distant tumor challenge.
Quick Facts
What This Study Found
Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vaccination effect) that protected against distant tumor challenge.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
Trust & Context
- Key Stat:
- Key finding Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vacc
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2010.
- Original Title:
- Therapeutic vaccination against a murine lymphoma by intratumoral injection of a cationic anticancer peptide.
- Published In:
- Cancer immunology, immunotherapy : CII, 59(8), 1285-94 (2010)
- Authors:
- Berge, Gerd(4), Eliassen, Liv Tone(4), Camilio, Ketil Andre, Bartnes, Kristian, Sveinbjørnsson, Baldur, Rekdal, Oystein
- Database ID:
- RPEP-01586
Evidence Hierarchy
Frequently Asked Questions
What was studied?
Injecting Anticancer Peptides Directly Into Tumors Creates a Vaccine-Like Anti-Cancer Immune Response
What was found?
Intratumoral injection of a cationic anticancer peptide not only killed local tumor cells but generated systemic anti-tumor immunity (therapeutic vaccination effect) that protected against distant tumor challenge.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01586APA
Berge, Gerd; Eliassen, Liv Tone; Camilio, Ketil Andre; Bartnes, Kristian; Sveinbjørnsson, Baldur; Rekdal, Oystein. (2010). Therapeutic vaccination against a murine lymphoma by intratumoral injection of a cationic anticancer peptide.. Cancer immunology, immunotherapy : CII, 59(8), 1285-94. https://doi.org/10.1007/s00262-010-0857-6
MLA
Berge, Gerd, et al. "Therapeutic vaccination against a murine lymphoma by intratumoral injection of a cationic anticancer peptide.." Cancer immunology, 2010. https://doi.org/10.1007/s00262-010-0857-6
RethinkPeptides
RethinkPeptides Research Database. "Therapeutic vaccination against a murine lymphoma by intratu..." RPEP-01586. Retrieved from https://rethinkpeptides.com/research/berge-2010-therapeutic-vaccination-against-a
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.