Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.
Quick Facts
What This Study Found
Oral bioavailability of peptides remains low, often in single digits, with high variability.
Key Numbers
How They Did This
The paper is a review that discusses various properties of peptides and their interactions with permeation enhancers.
Why This Research Matters
Improving oral bioavailability of peptides could enhance their therapeutic use, making them more accessible and effective for patients.
What This Study Doesn't Tell Us
As a review, it does not present original experimental data and may not cover all recent advancements in the field.
Trust & Context
- Original Title:
- Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.
- Published In:
- International journal of pharmaceutics, 628, 122238 (2022)
- Authors:
- Berg, Staffan, Edlund, Helena, R F Goundry, William, A S Bergström, Christel, Davies, Nigel M
- Database ID:
- RPEP-06010
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06010APA
Berg, Staffan; Edlund, Helena; R F Goundry, William; A S Bergström, Christel; Davies, Nigel M. (2022). Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.. International journal of pharmaceutics, 628, 122238. https://doi.org/10.1016/j.ijpharm.2022.122238
MLA
Berg, Staffan, et al. "Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.." International journal of pharmaceutics, 2022. https://doi.org/10.1016/j.ijpharm.2022.122238
RethinkPeptides
RethinkPeptides Research Database. "Considerations in the developability of peptides for oral ad..." RPEP-06010. Retrieved from https://rethinkpeptides.com/research/berg-2022-considerations-in-the-developability
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.