This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
Oral bioavailability of peptides remains low, often in single digits, with high variability.
Why it matters
Improving oral bioavailability of peptides could enhance their therapeutic use, making them more accessible and effective for patients.
How the study worked
The paper is a review that discusses various properties of peptides and their interactions with permeation enhancers.
What this study cannot tell us
As a review, it does not present original experimental data and may not cover all recent advancements in the field.
Read the original research
Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.
International journal of pharmaceutics, 628, 122238
Citation
Berg, Staffan; Edlund, Helena; R F Goundry, William; A S Bergström, Christel; Davies, Nigel M. (2022). Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers.. International journal of pharmaceutics, 628, 122238. https://doi.org/10.1016/j.ijpharm.2022.122238