Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know.
Quick Facts
What This Study Found
Liraglutide and semaglutide led to histological resolution of NASH in ~40% to 60% of patients.
Key Numbers
How They Did This
The study involved a review of existing literature and meta-analyses on GLP-1RAs and their effects on NASH.
Why This Research Matters
Understanding the role of GLP-1RAs in treating NASH could provide new therapeutic options for patients with limited treatment choices. This research may lead to improved management of obesity and related metabolic disorders.
What This Study Doesn't Tell Us
The review primarily summarizes existing studies, and the long-term effects and safety of GLP-1RAs in NASH require further investigation.
Trust & Context
- Original Title:
- Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know.
- Published In:
- Alimentary pharmacology & therapeutics, 55(8), 944-959 (2022)
- Authors:
- Barritt, A Sidney, Marshman, Emma, Noureddin, Mazen(5)
- Database ID:
- RPEP-06002
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-06002APA
Barritt, A Sidney; Marshman, Emma; Noureddin, Mazen. (2022). Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know.. Alimentary pharmacology & therapeutics, 55(8), 944-959. https://doi.org/10.1111/apt.16794
MLA
Barritt, A Sidney, et al. "Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know.." Alimentary pharmacology & therapeutics, 2022. https://doi.org/10.1111/apt.16794
RethinkPeptides
RethinkPeptides Research Database. "Review article: role of glucagon-like peptide-1 receptor ago..." RPEP-06002. Retrieved from https://rethinkpeptides.com/research/barritt-2022-review-article-role-of
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.