BPC-157 Prevents Digitalis-Induced Heart Arrhythmias Through the NO System
BPC-157 inhibited methyldigoxin-induced cardiac arrhythmias in rats through NO system modulation, demonstrating antiarrhythmic cardioprotective effects — adding heart rhythm protection to its cardiovascular profile.
Quick Facts
What This Study Found
BPC-157 prevented methyldigoxin-induced arrhythmias in rats through NO-system interaction (L-NAME attenuated, L-arginine enhanced the effect), demonstrating antiarrhythmic cardioprotection mediated by nitric oxide signaling — a new cardiovascular application.
Key Numbers
How They Did This
research study.
Why This Research Matters
Relevant for peptide research.
The Bigger Picture
Advances peptide research.
What This Study Doesn't Tell Us
See abstract.
Questions This Raises
- ?Further research needed.
- ?Clinical translation to evaluate.
Trust & Context
- Key Stat:
- Key finding BPC-157 prevented methyldigoxin-induced arrhythmias in rats through NO-system interaction (L-NAME attenuated, L-arginine enhanced the effect), demonst
- Evidence Grade:
- emerging evidence.
- Study Age:
- Published in 2009.
- Original Title:
- Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: a relation with NO-system.
- Published In:
- Regulatory peptides, 156(1-3), 83-9 (2009)
- Authors:
- Balenovic, Dijana, Bencic, Martina Lovric(3), Udovicic, Mario(3), Simonji, Karol, Hanzevacki, Jadranka Separovic, Barisic, Ivan, Kranjcevic, Stjepan, Prkacin, Ingrid, Coric, Vedran, Brcic, Luka, Coric, Marijana, Brcic, Iva, Borovic, Suzana, Radic, Bozo, Drmic, Domagoj, Vrcic, Hrvoje, Seiwerth, Sven, Sikiric, Predrag
- Database ID:
- RPEP-01452
Evidence Hierarchy
Frequently Asked Questions
What was studied?
BPC-157 Prevents Digitalis-Induced Heart Arrhythmias Through the NO System
What was found?
BPC-157 inhibited methyldigoxin-induced cardiac arrhythmias in rats through NO system modulation, demonstrating antiarrhythmic cardioprotective effects — adding heart rhythm protection to its cardiovascular profile.
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Cite This Study
https://rethinkpeptides.com/research/RPEP-01452APA
Balenovic, Dijana; Bencic, Martina Lovric; Udovicic, Mario; Simonji, Karol; Hanzevacki, Jadranka Separovic; Barisic, Ivan; Kranjcevic, Stjepan; Prkacin, Ingrid; Coric, Vedran; Brcic, Luka; Coric, Marijana; Brcic, Iva; Borovic, Suzana; Radic, Bozo; Drmic, Domagoj; Vrcic, Hrvoje; Seiwerth, Sven; Sikiric, Predrag. (2009). Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: a relation with NO-system.. Regulatory peptides, 156(1-3), 83-9. https://doi.org/10.1016/j.regpep.2009.05.008
MLA
Balenovic, Dijana, et al. "Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: a relation with NO-system.." Regulatory peptides, 2009. https://doi.org/10.1016/j.regpep.2009.05.008
RethinkPeptides
RethinkPeptides Research Database. "Inhibition of methyldigoxin-induced arrhythmias by pentadeca..." RPEP-01452. Retrieved from https://rethinkpeptides.com/research/balenovic-2009-inhibition-of-methyldigoxininduced-arrhythmias
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.