Study reveals endothelium- and fibroblast-derived CNP (C-type natriuretic peptide) prevents cardiac remodeling and heart failure through local paracrine signaling.
Key findingStudy reveals endothelium- and fibroblast-derived CNP (C-type natriuretic peptide) prevents cardiac
What the researchers found
Study reveals endothelium- and fibroblast-derived CNP (C-type natriuretic peptide) prevents cardiac remodeling and heart failure through local paracrine signaling.
Why it matters
Relevant to peptide therapeutics.
How the study worked
In publication.
What this study cannot tell us
In publication.
How to read the evidence
Based on design.
When this study was published
Published in 2025.
The bigger picture
Advances peptide evidence.
Questions still open
- Long-term implications?
- Evidence comparison?
- Next steps?
Common questions
What does this mean?
How reliable?
Read the original research
Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm.
Arteriosclerosis, thrombosis, and vascular biology, 45(7), 1044-1063
Citation
Aubdool, Aisah A; Moyes, Amie J; Perez-Ternero, Cristina; Baliga, Reshma S; Sanghera, Jaspinder Singh; Syed, M Taaha; Jaigirdar, Kareemah; Panesar, Anmolpreet K; Tsui, Janice C; Li, Yanming; Vasquez, Hernan G; Shen, Ying H; LeMaire, Scott A; Raffort, Juliette; Mallat, Ziad; Lu, Hong S; Daugherty, Alan; Hobbs, Adrian J. (2025). Endothelium- and Fibroblast-Derived C-Type Natriuretic Peptide Prevents the Development and Progression of Aortic Aneurysm.. Arteriosclerosis, thrombosis, and vascular biology, 45(7), 1044-1063. https://doi.org/10.1161/ATVBAHA.124.322350