GLP-1 Drugs for Opioid Addiction: A New Treatment Frontier
Review of GLP-1 drugs for opioid use disorder treatment examines evidence that these peptide drugs modulate reward circuits to reduce opioid craving and use.
Quick Facts
What This Study Found
Review of GLP-1 drugs for opioid use disorder treatment examines evidence that these peptide drugs modulate reward circuits to reduce opioid craving and use.
Key Numbers
How They Did This
In publication.
Why This Research Matters
Relevant to peptide therapeutics.
The Bigger Picture
Advances peptide evidence.
What This Study Doesn't Tell Us
In publication.
Questions This Raises
- ?Long-term implications?
- ?Evidence comparison?
- ?Next steps?
Trust & Context
- Key Stat:
- Key finding Review of GLP-1 drugs for opioid use disorder treatment examines evidence that these peptide drugs m
- Evidence Grade:
- Based on design.
- Study Age:
- Published in 2025.
- Original Title:
- Glucagon-like peptide-1 receptor agonists for the treatment of opioid use disorders: a systematic review.
- Published In:
- Acta neuropsychiatrica, 37, e85 (2025)
- Authors:
- Au, Hezekiah C T(5), Lam, Pak Ho(2), Kabir, Fateen, Huang, Chen Lily, Dri, Christine E, Le, Gia Han, Kwan, Angela T H, Wong, Sabrina, Teopiz, Kayla M, McIntyre, Roger S
- Database ID:
- RPEP-10011
Evidence Hierarchy
Frequently Asked Questions
What does this mean?
Review of GLP-1 drugs for opioid use disorder treatment examines evidence that these peptide drugs modulate reward circuits to reduce opioid craving and use.
How reliable?
Consult publication.
Read More on RethinkPeptides
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Cite This Study
https://rethinkpeptides.com/research/RPEP-10011APA
Au, Hezekiah C T; Lam, Pak Ho; Kabir, Fateen; Huang, Chen Lily; Dri, Christine E; Le, Gia Han; Kwan, Angela T H; Wong, Sabrina; Teopiz, Kayla M; McIntyre, Roger S. (2025). Glucagon-like peptide-1 receptor agonists for the treatment of opioid use disorders: a systematic review.. Acta neuropsychiatrica, 37, e85. https://doi.org/10.1017/neu.2025.10038
MLA
Au, Hezekiah C T, et al. "Glucagon-like peptide-1 receptor agonists for the treatment of opioid use disorders: a systematic review.." Acta neuropsychiatrica, 2025. https://doi.org/10.1017/neu.2025.10038
RethinkPeptides
RethinkPeptides Research Database. "Glucagon-like peptide-1 receptor agonists for the treatment ..." RPEP-10011. Retrieved from https://rethinkpeptides.com/research/au-2025-glucagonlike-peptide1-receptor-agonists
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.