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Study breakdown

Does GLP-1's Stomach-Slowing Effect Involve Amylin Release?

evidence
The takeaway

GLP-1's effects on gastric emptying, appetite, and food intake were investigated for amylin co-release involvement in humans, finding that GLP-1's actions are largely independent of amylin — separate satiety pathways.

Key finding

GLP-1's effects on gastric emptying, appetite, and food intake were investigated for amylin co-release involvement in humans, finding that GLP-1's act

What the researchers found

GLP-1's effects on gastric emptying, appetite, and food intake were investigated for amylin co-release involvement in humans, finding that GLP-1's actions are largely independent of amylin — separate satiety pathways.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Does GLP-1's Stomach-Slowing Effect Involve Amylin Release?
What was found?
GLP-1's effects on gastric emptying, appetite, and food intake were investigated for amylin co-release involvement in humans, finding that GLP-1's actions are largely independent of amylin — separate satiety pathways.

Read the original research

Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

The Journal of clinical endocrinology and metabolism, 95(5), 2367-75

Citation

Asmar, Meena; Bache, Michael; Knop, Filip K; Madsbad, Sten; Holst, Jens J. (2010). Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?. The Journal of clinical endocrinology and metabolism, 95(5), 2367-75. https://doi.org/10.1210/jc.2009-2133