Systematic review of vascular responses to molecular migraine triggers including CGRP characterizes how these peptides cause blood vessel changes that produce migraine pain.
Key findingSystematic review of vascular responses to molecular migraine triggers including CGRP characterizes
What the researchers found
Systematic review of vascular responses to molecular migraine triggers including CGRP characterizes how these peptides cause blood vessel changes that produce migraine pain.
Why it matters
Relevant to peptide therapeutics.
The numbers in context
Focused on middle meningeal artery (MMA) and middle cerebral artery (MCA). Multiple molecular triggers examined across available studies.
How the study worked
In publication.
Who was studied
Adults with migraine and healthy individuals in experimental MRA trigger studies
What this study cannot tell us
In publication.
How to read the evidence
Based on design.
When this study was published
Published in 2025.
The bigger picture
Advances peptide evidence.
Questions still open
- Long-term implications?
- Evidence comparison?
- Next steps?
Common questions
What does this mean?
How reliable?
Read the original research
Vascular responses to molecular migraine triggers: a systematic review of magnetic resonance angiography studies.
The journal of headache and pain, 26(1), 181
Citation
Arquizan, Robin; Melchior, Anna G; Christensen, Rune H; Al-Khazali, Haidar M; Ashina, Messoud; Ashina, Håkan. (2025). Vascular responses to molecular migraine triggers: a systematic review of magnetic resonance angiography studies.. The journal of headache and pain, 26(1), 181. https://doi.org/10.1186/s10194-025-02105-0