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Study breakdown

GLP-1 Drugs in Pregnancy: Obstetric and Perinatal Outcome Evaluation

Meta AnalysisModerate evidence
The takeaway

Evaluation of GLP-1 drug effects on obstetric and perinatal outcomes provides critical safety data for the growing number of pregnancies exposed to these drugs.

Key finding

Evaluation of GLP-1 drug effects on obstetric and perinatal outcomes provides critical safety data f

What the researchers found

Evaluation of GLP-1 drug effects on obstetric and perinatal outcomes provides critical safety data for the growing number of pregnancies exposed to these drugs.

Why it matters

Relevant to peptide therapeutics.

The numbers in context

Studies published 2020-2025 searched across PubMed, Embase, and Cochrane Central. Included RCTs and cohorts with control groups.

How the study worked

In publication.

Who was studied

Women exposed to GLP-1 receptor agonists during pregnancy or preconception

What this study cannot tell us

In publication.

How to read the evidence

Based on design.

When this study was published

Published in 2025.

The bigger picture

Advances peptide evidence.

Questions still open

  • Long-term implications?
  • Evidence comparison?
  • Next steps?

Common questions

What does this mean?
Evaluation of GLP-1 drug effects on obstetric and perinatal outcomes provides critical safety data for the growing number of pregnancies exposed to these drugs.
How reliable?
Consult publication.

Read the original research

Evaluation of GLP-1 receptor agonists in obstetrics and perinatal outcomes: A systematic review and meta-analysis.

Journal of gynecology obstetrics and human reproduction, 54(10), 103046

Citation

Armstrong, Bruna Benigna Sales; Servidoni, Ana Clara Pimenta; Martin, Giovanna Cristina de Castro; Machado, Guilherme Franceschini; Amador, Wellgner Fernandes Oliveira; Yousif, Abdelrahman. (2025). Evaluation of GLP-1 receptor agonists in obstetrics and perinatal outcomes: A systematic review and meta-analysis.. Journal of gynecology obstetrics and human reproduction, 54(10), 103046. https://doi.org/10.1016/j.jogoh.2025.103046