This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
Semaglutide reduced alcohol intake and relapse-like drinking in both male and female rats.
Why it matters
Understanding how semaglutide affects alcohol consumption could lead to new treatments for alcohol use disorder, especially in overweight patients.
How the study worked
The study used an intermittent access model to assess alcohol intake and relapse behaviors, alongside imaging techniques to observe semaglutide binding in the brain.
What this study cannot tell us
The study was conducted in rodents, and results may not directly translate to humans.
Read the original research
Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats.
EBioMedicine, 93, 104642
Citation
Aranäs, Cajsa; Edvardsson, Christian E; Shevchouk, Olesya T; Zhang, Qian; Witley, Sarah; Blid Sköldheden, Sebastian; Zentveld, Lindsay; Vallöf, Daniel; Tufvesson-Alm, Maximilian; Jerlhag, Elisabet. (2023). Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats.. EBioMedicine, 93, 104642. https://doi.org/10.1016/j.ebiom.2023.104642