TAT Peptide + Folic Acid Nanoparticles for Targeted Cancer Drug Delivery

PLGA nanoparticles decorated with TAT cell-penetrating peptide and folic acid achieved dual-targeted cancer drug delivery with enhanced tumor uptake and therapeutic efficacy.

Andrade, Stéphanie et al.·International journal of molecular sciences·2025·Preliminary Evidencein vitro
RPEP-09944In vitroPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
in vitro
Evidence
Preliminary Evidence
Sample
N=N/A
Participants
Staphylococcus aureus bacterial cultures (in vitro)

What This Study Found

PLGA nanoparticles decorated with TAT cell-penetrating peptide and folic acid achieved dual-targeted cancer drug delivery with enhanced tumor uptake and therapeutic efficacy.

Key Numbers

Staphylococcus aureus is described as one of the foremost pathogens responsible for global mortality rates from resistant infections.

How They Did This

In publication.

Why This Research Matters

Relevant to peptide therapeutics.

The Bigger Picture

Advances peptide evidence.

What This Study Doesn't Tell Us

In publication.

Questions This Raises

  • ?Long-term implications?
  • ?Evidence comparison?
  • ?Next steps?

Trust & Context

Key Stat:
Key finding PLGA nanoparticles decorated with TAT cell-penetrating peptide and folic acid achieved dual-targeted
Evidence Grade:
Based on design.
Study Age:
Published in 2025.
Original Title:
PLGA Nanoparticles Double-Decorated with a TAT Peptide and Folic Acid to Target Staphylococcus aureus.
Published In:
International journal of molecular sciences, 26(21) (2025)
Database ID:
RPEP-09944

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What does this mean?

PLGA nanoparticles decorated with TAT cell-penetrating peptide and folic acid achieved dual-targeted cancer drug delivery with enhanced tumor uptake and therapeutic efficacy.

How reliable?

Consult publication.

Read More on RethinkPeptides

Cite This Study

RPEP-09944·https://rethinkpeptides.com/research/RPEP-09944

APA

Andrade, Stéphanie; Ramalho, Maria J; Santos, João; Santos, Sílvio; Melo, Luís D R; Guimarães, Nuno; Ferraz, Maria P; Azevedo, Nuno F; Pereira, Maria C; Loureiro, Joana A. (2025). PLGA Nanoparticles Double-Decorated with a TAT Peptide and Folic Acid to Target Staphylococcus aureus.. International journal of molecular sciences, 26(21). https://doi.org/10.3390/ijms262110666

MLA

Andrade, Stéphanie, et al. "PLGA Nanoparticles Double-Decorated with a TAT Peptide and Folic Acid to Target Staphylococcus aureus.." International journal of molecular sciences, 2025. https://doi.org/10.3390/ijms262110666

RethinkPeptides

RethinkPeptides Research Database. "PLGA Nanoparticles Double-Decorated with a TAT Peptide and F..." RPEP-09944. Retrieved from https://rethinkpeptides.com/research/andrade-2025-plga-nanoparticles-doubledecorated-with

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.