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Study breakdown

VIP Peptide Puts T-Cells Into Cell Cycle Arrest and Activates Their Regulatory Functions

evidence
The takeaway

VIP induced cell cycle arrest in human T-cells while simultaneously activating regulatory (suppressive) functions, providing the cellular mechanism for VIP's immunosuppressive therapeutic effects.

Key finding

VIP induced cell cycle arrest in human T-cells while simultaneously activating regulatory (suppressive) functions, providing the cellular mechanism fo

What the researchers found

VIP induced cell cycle arrest in human T-cells while simultaneously activating regulatory (suppressive) functions, providing the cellular mechanism for VIP's immunosuppressive therapeutic effects.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
VIP Peptide Puts T-Cells Into Cell Cycle Arrest and Activates Their Regulatory Functions
What was found?
VIP induced cell cycle arrest in human T-cells while simultaneously activating regulatory (suppressive) functions, providing the cellular mechanism for VIP's immunosuppressive therapeutic effects.

Read the original research

Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels.

Molecular and cellular biology, 30(10), 2537-51

Citation

Anderson, Per; Gonzalez-Rey, Elena. (2010). Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels.. Molecular and cellular biology, 30(10), 2537-51. https://doi.org/10.1128/MCB.01282-09