C-Locked Analogs of the Antimicrobial Peptide BP214.
Quick Facts
What This Study Found
Analog 13 showed MIC = 4 µg/mL against E. coli and 36% hemolysis at 150 µM.
Key Numbers
How They Did This
The study involved synthesizing peptide analogs and testing their antimicrobial activity against various bacteria.
Why This Research Matters
The findings could lead to new treatments for infections caused by antibiotic-resistant bacteria, which are a growing public health concern.
What This Study Doesn't Tell Us
The study primarily focused on in vitro testing, which may not fully predict effectiveness in humans.
Trust & Context
- Original Title:
- C-Locked Analogs of the Antimicrobial Peptide BP214.
- Published In:
- Antibiotics (Basel, Switzerland), 11(8) (2022)
- Authors:
- Andersen, Ida Kristine Lysgaard, Thomsen, Thomas T, Rashid, Jasmina, Bobak, Thomas Rønnemoes, Oddo, Alberto, Franzyk, Henrik, Løbner-Olesen, Anders, Hansen, Paul R
- Database ID:
- RPEP-05986
Evidence Hierarchy
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Cite This Study
https://rethinkpeptides.com/research/RPEP-05986APA
Andersen, Ida Kristine Lysgaard; Thomsen, Thomas T; Rashid, Jasmina; Bobak, Thomas Rønnemoes; Oddo, Alberto; Franzyk, Henrik; Løbner-Olesen, Anders; Hansen, Paul R. (2022). C-Locked Analogs of the Antimicrobial Peptide BP214.. Antibiotics (Basel, Switzerland), 11(8). https://doi.org/10.3390/antibiotics11081080
MLA
Andersen, Ida Kristine Lysgaard, et al. "C-Locked Analogs of the Antimicrobial Peptide BP214.." Antibiotics (Basel, 2022. https://doi.org/10.3390/antibiotics11081080
RethinkPeptides
RethinkPeptides Research Database. "C-Locked Analogs of the Antimicrobial Peptide BP214." RPEP-05986. Retrieved from https://rethinkpeptides.com/research/andersen-2022-clocked-analogs-of-the
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.