DOTATATE PRRT for Neuroendocrine Tumors: South Australian Clinical Experience

South Australian experience with 177Lu-DOTATATE peptide receptor radionuclide therapy for neuroendocrine tumors provides real-world efficacy and safety data for this somatostatin-based treatment.

Altus, L M et al.·ESMO gastrointestinal oncology·2025·Moderate Evidencecohort
RPEP-09913CohortModerate Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
cohort
Evidence
Moderate Evidence
Sample
N=medium
Participants
189 patients with metastatic or advanced neuroendocrine tumors treated at an Australian hospital (2011-2022)

What This Study Found

South Australian experience with 177Lu-DOTATATE peptide receptor radionuclide therapy for neuroendocrine tumors provides real-world efficacy and safety data for this somatostatin-based treatment.

Key Numbers

189 patients treated over 11 years (2011-2022). Assessed for toxicity, radiological response, quality of life, and survival.

How They Did This

In publication.

Why This Research Matters

Relevant to peptide therapeutics.

The Bigger Picture

Advances peptide therapeutic knowledge.

What This Study Doesn't Tell Us

In publication.

Questions This Raises

  • ?Long-term implications?
  • ?Comparison to evidence?
  • ?Next research?

Trust & Context

Key Stat:
Key finding South Australian experience with 177Lu-DOTATATE peptide receptor radionuclide therapy for neuroendoc
Evidence Grade:
Based on study design.
Study Age:
Published in 2025.
Original Title:
The South Australian 177Lu-DOTATATE peptide receptor radionuclide therapy service: an 11-year review of toxicity, health-related quality of life, and survival.
Published In:
ESMO gastrointestinal oncology, 8, 100146 (2025)
Database ID:
RPEP-09913

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What does this mean?

South Australian experience with 177Lu-DOTATATE peptide receptor radionuclide therapy for neuroendocrine tumors provides real-world efficacy and safety data for this somatostatin-based treatment.

How reliable?

Consult publication.

Read More on RethinkPeptides

Cite This Study

RPEP-09913·https://rethinkpeptides.com/research/RPEP-09913

APA

Altus, L M; Forster, J C; Mercurio, J; Kitchener, M; Corsini, N; Nenke, M; Price, T; Patel, D; Chew, R; Moffat, D; Unger, S; Cehic, G. (2025). The South Australian 177Lu-DOTATATE peptide receptor radionuclide therapy service: an 11-year review of toxicity, health-related quality of life, and survival.. ESMO gastrointestinal oncology, 8, 100146. https://doi.org/10.1016/j.esmogo.2025.100146

MLA

Altus, L M, et al. "The South Australian 177Lu-DOTATATE peptide receptor radionuclide therapy service: an 11-year review of toxicity, health-related quality of life, and survival.." ESMO gastrointestinal oncology, 2025. https://doi.org/10.1016/j.esmogo.2025.100146

RethinkPeptides

RethinkPeptides Research Database. "The South Australian 177Lu-DOTATATE peptide receptor radionu..." RPEP-09913. Retrieved from https://rethinkpeptides.com/research/altus-2025-the-south-australian-177ludotatate

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.