Novel nano-delivery system combining colchicine with peptide nanoparticles achieved targeted anti-inflammatory drug delivery with improved efficacy and reduced side effects.
Key findingNovel nano-delivery system combining colchicine with peptide nanoparticles achieved targeted anti-in
What the researchers found
Novel nano-delivery system combining colchicine with peptide nanoparticles achieved targeted anti-inflammatory drug delivery with improved efficacy and reduced side effects.
Why it matters
Relevant to peptide-based therapeutic applications.
The numbers in context
Colchicine-loaded lipid nanocapsules conjugated with NFL-TBS.40-63 peptide. Tested for selective glioblastoma cell targeting and cytotoxicity.
How the study worked
Methodology in publication.
Who was studied
In vitro glioblastoma cell line experiments
What this study cannot tell us
Limitations in publication.
How to read the evidence
Based on study design.
When this study was published
Published in 2025.
The bigger picture
Contributes to peptide therapeutic evidence.
Questions still open
- Long-term implications?
- Comparison to evidence?
- Next research?
Common questions
What does this mean?
How reliable?
Read the original research
Development of a potential nano-based delivery system combining Colchicine-loaded lipid nanocapsules and BIOT-NFL-peptide to target glioblastoma.
International journal of pharmaceutics: X, 10, 100382
Citation
Alnemeh-Al Ali, H; Bejaud, J; Lautram, N; Dupont, A; Eyer, J. (2025). Development of a potential nano-based delivery system combining Colchicine-loaded lipid nanocapsules and BIOT-NFL-peptide to target glioblastoma.. International journal of pharmaceutics: X, 10, 100382. https://doi.org/10.1016/j.ijpx.2025.100382