NPY Expression Changes With Aging in the Brain's Inferior Colliculus

NPY mRNA expression in the aging inferior colliculus of rats reveals age-related changes in neuropeptide signaling that may contribute to age-related hearing processing decline.

Almassri, Laila S et al.·Frontiers in aging neuroscience·2025·Preliminary Evidenceanimal study
RPEP-09883Animal studyPreliminary Evidence2025RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
animal study
Evidence
Preliminary Evidence
Sample
N=small
Participants
Fischer Brown Norway rats across different age groups

What This Study Found

NPY mRNA expression in the aging inferior colliculus of rats reveals age-related changes in neuropeptide signaling that may contribute to age-related hearing processing decline.

Key Numbers

NPY mRNA measured across age groups in Fischer Brown Norway rats, showing progressive decline in the inferior colliculus.

How They Did This

Methodology detailed in publication.

Why This Research Matters

Relevant to expanding peptide-based therapeutic applications.

The Bigger Picture

Contributes to the growing evidence for peptide therapeutics.

What This Study Doesn't Tell Us

Limitations in publication.

Questions This Raises

  • ?Long-term implications?
  • ?Comparison to existing evidence?
  • ?Next research steps?

Trust & Context

Key Stat:
Key finding NPY mRNA expression in the aging inferior colliculus of rats reveals age-related changes in neuropep
Evidence Grade:
Based on study design in publication.
Study Age:
Published in 2025.
Original Title:
Neuropeptide Y mRNA expression in the aging inferior colliculus of fischer brown norway rats.
Published In:
Frontiers in aging neuroscience, 17, 1626021 (2025)
Database ID:
RPEP-09883

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / ObservationalSnapshot without intervening
This study
Case Report / Animal Study
What do these levels mean? →

Frequently Asked Questions

What does this mean?

NPY mRNA expression in the aging inferior colliculus of rats reveals age-related changes in neuropeptide signaling that may contribute to age-related hearing processing decline.

How reliable?

Consult publication and healthcare provider.

Read More on RethinkPeptides

Cite This Study

RPEP-09883·https://rethinkpeptides.com/research/RPEP-09883

APA

Almassri, Laila S; Crane, Kristen M; Hergenrother, Sean R; Singh, Gurveer; Barach, Gillian L; Iafrate, Melina C; Harris, Joshua C; Tokar, Nick; Ohl, Andrew P; Young, Jesse W; Mellott, Jeffrey G. (2025). Neuropeptide Y mRNA expression in the aging inferior colliculus of fischer brown norway rats.. Frontiers in aging neuroscience, 17, 1626021. https://doi.org/10.3389/fnagi.2025.1626021

MLA

Almassri, Laila S, et al. "Neuropeptide Y mRNA expression in the aging inferior colliculus of fischer brown norway rats.." Frontiers in aging neuroscience, 2025. https://doi.org/10.3389/fnagi.2025.1626021

RethinkPeptides

RethinkPeptides Research Database. "Neuropeptide Y mRNA expression in the aging inferior collicu..." RPEP-09883. Retrieved from https://rethinkpeptides.com/research/almassri-2025-neuropeptide-y-mrna-expression

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.