Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why GLP-1 drugs affect so many organ systems.
Key findingStudy maps GLP-1 receptor expression and functional diversity across human tissues, explaining why G
What the researchers found
Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why GLP-1 drugs affect so many organ systems.
Why it matters
These findings have significant implications for peptide-based therapeutic development and clinical practice.
The numbers in context
Analysis used TCGA and GTEx databases covering multiple cancer types with thousands of tumor samples.
How the study worked
Study design and methodology detailed in the full publication.
Who was studied
Tumor samples across multiple cancer types from TCGA and GTEx databases
What this study cannot tell us
Study-specific limitations discussed in the full publication. Results should be interpreted within the context of study design.
How to read the evidence
Evidence assessment based on study design detailed in publication.
When this study was published
Published in 2025. Current peptide therapeutic research.
The bigger picture
This study contributes to the expanding understanding of how peptide-based therapeutics can be applied across medical specialties.
Questions still open
- What are the long-term implications?
- How do these results compare to existing evidence?
- What further research is needed?
Common questions
What does this study mean for patients?
How reliable are these findings?
Read the original research
Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types.
Discover oncology, 17(1), 36
Citation
Alba, Mario M; Lee, Wilson H; Lee, Jerry S H; Lu, Zhipeng; Stiles, Bangyan; Ligumsky, Hagai. (2025). Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types.. Discover oncology, 17(1), 36. https://doi.org/10.1007/s12672-025-04097-4