GLP-1 Receptor Expression Across Body Tissues: Why These Drugs Have So Many Effects
Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why GLP-1 drugs affect so many organ systems.
Quick Facts
What This Study Found
Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why GLP-1 drugs affect so many organ systems.
Key Numbers
Analysis used TCGA and GTEx databases covering multiple cancer types with thousands of tumor samples.
How They Did This
Study design and methodology detailed in the full publication.
Why This Research Matters
These findings have significant implications for peptide-based therapeutic development and clinical practice.
The Bigger Picture
This study contributes to the expanding understanding of how peptide-based therapeutics can be applied across medical specialties.
What This Study Doesn't Tell Us
Study-specific limitations discussed in the full publication. Results should be interpreted within the context of study design.
Questions This Raises
- ?What are the long-term implications?
- ?How do these results compare to existing evidence?
- ?What further research is needed?
Trust & Context
- Key Stat:
- Key finding Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why G
- Evidence Grade:
- Evidence assessment based on study design detailed in publication.
- Study Age:
- Published in 2025. Current peptide therapeutic research.
- Original Title:
- Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types.
- Published In:
- Discover oncology, 17(1), 36 (2025)
- Authors:
- Alba, Mario M, Lee, Wilson H, Lee, Jerry S H, Lu, Zhipeng, Stiles, Bangyan, Ligumsky, Hagai
- Database ID:
- RPEP-09841
Evidence Hierarchy
Summarizes existing research on a topic.
What do these levels mean? →Frequently Asked Questions
What does this study mean for patients?
Study maps GLP-1 receptor expression and functional diversity across human tissues, explaining why GLP-1 drugs affect so many organ systems.
How reliable are these findings?
Evidence strength depends on study design. Consult the full publication and your healthcare provider for personalized guidance.
Read More on RethinkPeptides
Cite This Study
https://rethinkpeptides.com/research/RPEP-09841APA
Alba, Mario M; Lee, Wilson H; Lee, Jerry S H; Lu, Zhipeng; Stiles, Bangyan; Ligumsky, Hagai. (2025). Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types.. Discover oncology, 17(1), 36. https://doi.org/10.1007/s12672-025-04097-4
MLA
Alba, Mario M, et al. "Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types.." Discover oncology, 2025. https://doi.org/10.1007/s12672-025-04097-4
RethinkPeptides
RethinkPeptides Research Database. "Expression and functional diversity of the glucagon-like pep..." RPEP-09841. Retrieved from https://rethinkpeptides.com/research/alba-2025-expression-and-functional-diversity
Access the Original Study
Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.
This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.