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Low Ghrelin in the Uterine Lining May Contribute to Female Infertility

evidence
The takeaway

Diminished endometrial ghrelin and GHS-R expression was associated with infertility in women, suggesting the uterine ghrelin system is necessary for successful embryo implantation and early pregnancy.

Key finding

Diminished endometrial ghrelin and GHS-R expression was associated with infertility in women, suggesting the uterine ghrelin system is necessary for s

What the researchers found

Diminished endometrial ghrelin and GHS-R expression was associated with infertility in women, suggesting the uterine ghrelin system is necessary for successful embryo implantation and early pregnancy.

Why it matters

Relevant for peptide research.

How the study worked

research study.

What this study cannot tell us

See abstract.

How to read the evidence

emerging evidence.

When this study was published

Published in 2010.

The bigger picture

Advances peptide research.

Questions still open

  • Further research needed.

Common questions

What was studied?
Low Ghrelin in the Uterine Lining May Contribute to Female Infertility
What was found?
Diminished endometrial ghrelin and GHS-R expression was associated with infertility in women, suggesting the uterine ghrelin system is necessary for successful embryo implantation and early pregnancy.

Read the original research

Diminished endometrial expression of ghrelin and ghrelin receptor contributes to infertility.

Reproductive sciences (Thousand Oaks, Calif.), 17(9), 823-32

Citation

Aghajanova, Lusine; Rumman, Amani; Altmäe, Signe; Wånggren, Kjell; Stavreus-Evers, Anneli. (2010). Diminished endometrial expression of ghrelin and ghrelin receptor contributes to infertility.. Reproductive sciences (Thousand Oaks, Calif.), 17(9), 823-32. https://doi.org/10.1177/1933719110371683