Fractionated chicken by-product protein hydrolysates showed enhanced antihypertensive activity, with separated peptide fractions more potent than the original mixture for ACE inhibition.
Waste to medicineChicken processing by-products yielded potent ACE-inhibitory peptides after enzymatic digestion and fractionation
What the researchers found
Fractionated chicken by-product hydrolysates showed enhanced ACE-inhibitory activity compared to the unfractionated mixture, identifying specific peptide fractions with potent antihypertensive properties.
Why it matters
Converting food waste into health-promoting peptides addresses both sustainability and health goals. Chicken processing by-products could become a source of affordable blood pressure-lowering supplements.
The numbers in context
Peptide separation was based on charge and molecular weight using EDUF. Specific ACE-inhibitory activity measurements were compared across fractions.
How the study worked
Enzymatic hydrolysis of chicken by-product proteins. Separation of hydrolysate into fractions. Assessment of ACE-inhibitory activity and antihypertensive peptide characterization.
Who was studied
N/A — in vitro peptide separation and characterization study
What this study cannot tell us
In vitro ACE inhibition study. In vivo blood pressure effects in animals or humans not tested. Peptide stability through human digestion needs evaluation.
How to read the evidence
Preliminary evidence: in vitro ACE inhibition study with peptide fractionation. No in vivo blood pressure data.
When this study was published
Published in 2025. Advances food waste upcycling into bioactive peptide products.
The bigger picture
Upcycling food industry waste into bioactive peptides is a growing field that addresses both environmental sustainability and public health. Chicken by-products join dairy, fish, and plant proteins as sources of heart-healthy peptides.
Questions still open
- Would consuming these peptide fractions lower blood pressure in human studies?
- Can the separation process be scaled for commercial production?
- How do chicken-derived antihypertensive peptides compare to dairy-derived alternatives?
Common questions
Can chicken by-products lower blood pressure?
How is food waste turned into health products?
Read the original research
Enhanced antihypertensive chicken by-product hydrolysate fraction after its separation by electrodialysis with ultrafiltration membrane (EDUF).
Food research international (Ottawa, Ont.), 202, 115595
Citation
Adaile-Pérez, Vianey Monsserrat; Thibodeau, Jacinthe; Ortiz-Basurto, Rosa Isela; de Lourdes García-Magaña, María; Bazinet, Laurent. (2025). Enhanced antihypertensive chicken by-product hydrolysate fraction after its separation by electrodialysis with ultrafiltration membrane (EDUF).. Food research international (Ottawa, Ont.), 202, 115595. https://doi.org/10.1016/j.foodres.2024.115595