Ipamorelin Improves Nitrogen Balance in Steroid-Treated Rats: Better Than GH Alone

Ipamorelin improved nitrogen balance and reduced urea synthesis in steroid-treated rats comparably to GH, demonstrating the GH secretagogue can counteract steroid-induced protein wasting as effectively as direct GH replacement.

RPEP-01448Animal StudyPreliminary Evidence2009RETHINKTHC RESEARCH DATABASErethinkthc.com/research

Quick Facts

Study Type
Animal Study
Evidence
Preliminary Evidence
Sample
Not reported

What This Study Found

Ipamorelin improved nitrogen balance and reduced urea synthesis in dexamethasone-treated rats comparably to GH injection, demonstrating GH secretagogue equivalence to direct GH for counteracting steroid-induced protein catabolism.

Key Numbers

How They Did This

animal-study study.

Why This Research Matters

Relevant for ipamorelin, hormone-optimization, muscle-recovery.

The Bigger Picture

Advances peptide research.

What This Study Doesn't Tell Us

See abstract.

Questions This Raises

  • ?Further research needed.
  • ?Clinical translation to evaluate.

Trust & Context

Key Stat:
Key finding Ipamorelin improved nitrogen balance and reduced urea synthesis in dexamethasone-treated rats comparably to GH injection, demonstrating GH secretagogu
Evidence Grade:
preliminary evidence.
Study Age:
Published in 2009.
Original Title:
Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats.
Published In:
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 19(5), 426-31 (2009)
Database ID:
RPEP-01448

Evidence Hierarchy

Meta-Analysis / Systematic Review
Randomized Controlled Trial
Cohort / Case-Control
Cross-Sectional / Observational
Case Report / Animal StudyOne case or non-human subjects
This study

Tests effects in animals (usually mice or rats), not humans.

What do these levels mean? →

Frequently Asked Questions

What was studied?

Ipamorelin Improves Nitrogen Balance in Steroid-Treated Rats: Better Than GH Alone

What was found?

Ipamorelin improved nitrogen balance and reduced urea synthesis in steroid-treated rats comparably to GH, demonstrating the GH secretagogue can counteract steroid-induced protein wasting as effectively as direct GH replacement.

Read More on RethinkPeptides

Cite This Study

RPEP-01448·https://rethinkpeptides.com/research/RPEP-01448

APA

Aagaard, Niels Kristian; Grøfte, Thorbjørn; Greisen, Jacob; Malmlöf, Kjell; Johansen, Peter B; Grønbaek, Henning; Ørskov, Hans; Tygstrup, Niels; Vilstrup, Hendrik. (2009). Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats.. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 19(5), 426-31. https://doi.org/10.1016/j.ghir.2009.01.001

MLA

Aagaard, Niels Kristian, et al. "Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats.." Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2009. https://doi.org/10.1016/j.ghir.2009.01.001

RethinkPeptides

RethinkPeptides Research Database. "Growth hormone and growth hormone secretagogue effects on ni..." RPEP-01448. Retrieved from https://rethinkpeptides.com/research/aagaard-2009-growth-hormone-and-growth

Access the Original Study

Study data sourced from PubMed, a service of the U.S. National Library of Medicine, National Institutes of Health.

This study breakdown was produced by the RethinkPeptides research team. We analyze and report published research findings without making health recommendations. All interpretations are based solely on the published abstract and study data.