Sirtuins and Peptide Longevity
2 articles in this topic.
Sirtuins and Peptide Longevity
Where NAD+ and Peptide Longevity Pathways Intersect
NAD+ decline drives aging. Mitochondrial peptides like MOTS-c and humanin regulate NAD+ metabolism. Here's how these longevity pathways connect.
13 min read|Mar 26, 2026
Sirtuins and Peptide Longevity
MOTS-c and NAD+: Where Mitochondrial Peptides Meet Energy
MOTS-c is a 16-amino-acid mitochondrial peptide that activates AMPK by disrupting folate-linked NAD+ metabolism. Full evidence review.
13 min read|Mar 22, 2026