Leptin
3 articles in this topic.
Leptin
The Leptin-Melanocortin Pathway: How Satiety Signals Work
The leptin-melanocortin pathway converts fat-stored energy signals into appetite suppression through POMC neurons, alpha-MSH, and MC4R in the hypothalamus.
15 min read|Mar 25, 2026
Leptin
Metreleptin: The FDA-Approved Leptin Analog
Metreleptin (Myalept) replaces missing leptin in generalized lipodystrophy, reducing HbA1c, triglycerides, and liver fat. Full clinical data review.
13 min read|Mar 22, 2026
Leptin
Congenital Leptin Deficiency: The Condition That Proved Leptin's Role
Congenital leptin deficiency affects roughly 1 in 15 million people, but its discovery proved leptin controls hunger in humans. Here is the full story.
13 min read|Mar 21, 2026