Gut-Brain Peptide Signaling

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The Vagus Nerve: How Gut Peptides Talk to Your Brain

The vagus nerve carries peptide signals from gut to brain, controlling appetite, mood, and metabolism. A research-backed guide to this critical pathway.

18 min read|Mar 20, 2026

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Gut-Brain Peptide Signaling

The Hypothalamic Feeding Circuit: Peptides That Flip Hunger

AgRP and NPY drive hunger. POMC and alpha-MSH drive satiety. This is how opposing peptide neurons in the arcuate nucleus control whether you eat or stop.

12 min read|Mar 25, 2026