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AMP Mechanisms

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AMP MechanismsGuide

How Antimicrobial Peptides Kill Bacteria

AMPs kill bacteria through pore formation, membrane disruption, and intracellular targeting. The barrel-stave, toroidal, and carpet models explained.

18 min read|Mar 20, 2026

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AMP Mechanisms

Barrel-Stave, Toroidal, and Carpet Models of AMP Action

How antimicrobial peptides destroy bacterial membranes through three distinct mechanisms: barrel-stave pores, toroidal pores, and carpet-model disruption.

16 min read|Mar 25, 2026
AMP Mechanisms

Beyond Membrane Disruption: AMPs That Hit Inside

Some antimicrobial peptides kill bacteria by targeting DNA, ribosomes, and protein folding inside the cell, not just by punching holes in membranes.

11 min read|Mar 21, 2026

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